Office of Undergraduate Instruction

01:447:481 Topics in Human Genetics

This course may be used to fulfill the elective requirements of the Biological Sciences major.






Genetics 01:447:380r Genetic Analysis I 01:447:384. Requires departmental permission to register.

Course Description

This is a foundational graduate course in human genetics, covering classical and non-classical patterns of inheritance, human genome structure and evolution, normal and abnormal processes of gene expression, molecular genetic pathology, laboratory methods for genetic analysis, and research approaches to the study of human genetic disease using humans and model organisms. There will be homework assignments, a midterm and final. The course is cross-listed with 16:681:535 (Graduate Human Genetics); thus, student taking the course will comprise a mixture of senior undergraduates and graduate students.

Course URL (login with your Rutgers NetID)

Course Goals

The goals of this Human Genetics course are to provide students a foundation in the key biological concepts and experimental methodologies of human genetics. Specific course objectives
are to:

1.Comprehend and apply knowledge of human genetics as it relates to a variety of topics
including inheritance patterns, population and quantitative genetics, and epigenetics

2. Appreciate a variety of genetic and genomic testing technologies and understand their application and utility, in both research and clinical settings

3. Understand the basis of human variation and disease

4.Understand the utility and limitations of model organism research and how such work leads to advances in the understanding and treatment of human genetic disease

Course Satisfies Departmental Learning Goals

1. Knowledge specific goals: Know the terms, concepts and theories in genetics

2. Integrate the material from multiple courses and research.
That is, to think holistically and to see the whole as well as the parts

3. Use genetic information and ideas to critically analyze
published research articles in genetics.

4. Be able to communicate scientific research through written
papers and verbal presentations.

Exams, Assignments, and Grading Policy

35% Homeworks and class presenta

60% Lecture-based Problem Sets

20% Final exam

Course Materials

Human Molecular Genetics, 4th ed. By Tom Strachan and Andrew Read
ISBN-10: 0815341490
ISBN-13: 978-081534149-9

Course Closed?

If the course is closed, please use the following link to ad your name to the wait list: Wait List Sign Up for Fall 2015 Courses . If you have any questions, please contact Kathleen McDonald in the Genetics Undergraduate Office (This email address is being protected from spambots. You need JavaScript enabled to view it.This email address is being protected from spambots. You need JavaScript enabled to view it.


Tara Matise, Ph.D., Course Coordinator
Office: Nelson C205
Phone: 848-445-3125

** All information is subject to change at the discretion of the course coordinator.

Contact Us

Nelson Biological Laboratories

Nelson Biological Laboratories
604 Allison Rd
Piscataway, NJ 08854

p. (848) 445-2075
f.  (732) 445-5870